Retail

Retail Space on East 110th Street – 202-204 E 110th Street, East Harlem / Spanish Harlem

Address: 202-204 East 110th Street, New York, NY, 10029
Price: $13,000/month
Square Feet: 3,000 SF
Type: Retail Space

Property Overview:

Located on East 110th Street in East Harlem (also known as El Barrio or Spanish Harlem) — one of Manhattan’s most culturally rich, vibrant, and rapidly evolving neighborhoods — 202-204 E 110th Street offers 3,000 SF of spacious retail space at exceptional value for this prime location. Ideal for fitness centers, medical and dental practices, urgent care centers, pharmacies, specialty food markets, community-focused retail, or service-based businesses. Situated between Second Avenue and Third Avenue, this space benefits from proximity to Central Park, the East River waterfront, major hospitals, and some of the city’s best authentic Latin dining, shopping, and transit.

Key Features:

Prime East Harlem / Spanish Harlem / El Barrio Location:

• Situated on East 110th Street, a vibrant east-west thoroughfare at the southern gateway to East Harlem (also known as El Barrio or Spanish Harlem) — one of Manhattan’s most culturally rich, vibrant, and rapidly evolving neighborhoods, known for its authentic Latin cuisine (Puerto Rican, Mexican, Dominican), community gardens, street art, strong sense of community, and rich cultural heritage.
• Located between Second Avenue and Third Avenue, placing your business in a densely populated residential and commercial corridor with strong community ties, steady foot traffic, and growing investment.
• Just steps from Central Park (entrance at 110th Street and Fifth Avenue), offering 843 acres of green space, walking paths, playgrounds, and iconic attractions — generating foot traffic from joggers, dog walkers, families, and tourists.
• Minutes from Museum Mile (Fifth Avenue from 82nd to 105th Streets), home to the Metropolitan Museum of Art (The Met), Guggenheim Museum, Neue Galerie, and Jewish Museum.
• Close to Mount Sinai Medical Center (98th-101st Streets on Madison/Fifth Avenues), NYC Health + Hospitals/Metropolitan (97th Street and First Avenue), and the East River Waterfront.

High-Traffic, Rapidly Evolving Corridor:

• East 110th Street between Second and Third Avenues is a busy residential and commercial corridor, drawing a mix of local residents, families, medical professionals, students, Central Park visitors, and museum-goers.
• The area is known for its strong daytime foot traffic from residents running errands, medical professionals, and students, plus strong evening and weekend traffic from families, park visitors, and diners.
• The neighborhood’s strong sense of community and loyalty to local businesses make it ideal for businesses that rely on repeat clientele and word-of-mouth referrals.
• East Harlem has seen significant new development in recent years, adding new residential buildings, retail, and improving public spaces — making this an opportune time to establish a presence.

Spacious & Flexible Retail Layout – 3,000 SF:

• 3,000 SF of generous retail space — ideally sized for a fitness center, medical or dental practice, urgent care center, physical therapy clinic, pharmacy, specialty food market, or community-focused retail.
• Attractive storefront with excellent street-level visibility on East 110th Street, a busy corridor with constant pedestrian and vehicular flow.
• High ceilings and open floor plan with minimal columns, allowing for easy customization to fit various business needs — from fitness equipment and exam rooms to retail displays and checkouts.
• Large windows providing abundant natural light — a valuable feature for patient-facing medical practices and wellness studios.
• Potential for back-of-house space, storage, or office areas depending on configuration.
• At $4.33 per square foot, this represents exceptional value for retail space in this rapidly developing Upper Manhattan neighborhood.

Exceptional Value – Under $4.35 per Square Foot:

• At $4.33 per square foot, this is an extraordinary value for a 3,000 SF retail space in East Harlem — one of the most affordable rates for large-format retail in Manhattan.
• The combination of price, location, space, and growth potential makes this an unparalleled opportunity.

Excellent Transit Access:

• Moments from the 110th Street subway station (6) on Lexington Avenue — a 5-minute walk — providing direct access to the entire East Side of Manhattan and Grand Central Terminal.
• Close to the 116th Street station (6) , Central Park North station (2, 3) at 110th Street and Lenox Avenue, and 103rd Street station (6) .
• Multiple bus routes serve Third Avenue, Lexington Avenue, and 110th Street (M1, M2, M3, M4, M106, M116).
• Short walk to the Metro-North Railroad at Harlem-125th Street station (Hudson, Harlem, and New Haven lines), providing direct access to Westchester, Connecticut, and the Bronx.
• Convenient for commuters to Midtown, the Financial District, and beyond.

Diverse, High-Demand Customer Base:

• Local residents — East Harlem is home to a diverse, dense population of longtime residents (primarily Puerto Rican, Mexican, Dominican, and other Latin American communities), as well as young professionals, families, and artists.
• Medical professionals and patients — proximity to Mount Sinai Medical Center and NYC Health + Hospitals/Metropolitan creates consistent demand for medical practices, urgent care, pharmacies, and patient-serving retail.
• Central Park and Museum visitors — millions of annual visitors to Central Park and Museum Mile generate foot traffic, particularly on weekends and holidays.
• Columbia University students and faculty — the nearby Columbia University campus (116th Street and Broadway) brings thousands of students, faculty, and staff to the area.
• Ideal for businesses such as:
• Fitness center (gym, yoga, Pilates, cycling)
• Medical or dental practice (primary care, pediatrics, dermatology, dentistry)
• Urgent care or walk-in clinic
• Physical therapy or rehabilitation center
• Pharmacy or drugstore
• Specialty food market (Latin groceries, fresh produce)
• Beauty or nail salon
• Coffee shop or cafe
• Community-focused retail or social enterprise
• Daycare or children’s enrichment center

Highlights:
✔ 3,000 SF of spacious retail space in East Harlem / Spanish Harlem
✔ $13,000/month — exceptional value at just $4.33 per square foot
✔ Attractive storefront with excellent visibility on a busy residential corridor
✔ Steps from Central Park, Museum Mile, and Mount Sinai Medical Center
✔ High ceilings and open floor plan — ideal for fitness, medical, pharmacy, or market
✔ Ideal for fitness center, medical/dental practice, urgent care, or specialty food market
✔ Large windows with abundant natural light
✔ Diverse, loyal, high-demand customer base — residents, medical professionals, park visitors, and museum-goers
✔ Excellent transit access — 6, 2, 3 trains and multiple bus routes
✔ Rapidly developing neighborhood with strong community ties

Conclusion:

202-204 E 110th Street offers an exceptional opportunity for healthcare providers, fitness operators, and small business owners seeking affordable, spacious retail space in one of Manhattan’s most culturally rich, vibrant, and rapidly evolving neighborhoods — East Harlem / Spanish Harlem, steps from Central Park, Museum Mile, and Mount Sinai Medical Center. With 3,000 SF of functional, flexible space, a prime East 110th Street location in the heart of a densely populated residential and medical corridor, and access to a loyal, high-demand customer base of residents, medical professionals, park visitors, and museum-goers, this property is perfect for fitness centers, medical and dental practices, urgent care centers, pharmacies, or specialty food markets looking to thrive in a neighborhood that beautifully balances authentic cultural heritage with modern growth and development — all at an extraordinary value of just over $4 per square foot.

Contact us today to schedule a private tour and secure this premier East Harlem retail space.