Retail

Prime Retail Space on East 61st Street – 252 E 61st Street, Lenox Hill / Upper East Side

Address: 252 E 61st Street, New York, NY, 10065
Price: $30,000/month
Square Feet: 1,058 SF
Type: Retail Space

Property Overview:

Located on East 61st Street in the prestigious Lenox Hill neighborhood of the Upper East Side, 252 E 61st Street offers 1,058 SF of prime retail space at a premium price befitting this affluent residential and medical corridor. Ideal for medical and dental practices, urgent care centers, physical therapy clinics, pharmacies, beauty salons, specialty food shops, or service-based businesses. Situated between Second Avenue and Third Avenue, this space benefits from proximity to world-class hospitals (Weill Cornell, NY-Presbyterian, HSS, Memorial Sloan Kettering), luxury residential buildings, and some of the city’s best dining, shopping, and transit.

Key Features:

Prime Lenox Hill / Upper East Side Location:

• Situated on East 61st Street, a quiet, tree-lined residential block in the heart of Lenox Hill — one of the Upper East Side’s most desirable and prestigious neighborhoods, known for its pre-war architecture, luxury residential buildings, and proximity to world-class medical institutions.
• Located between Second Avenue and Third Avenue, placing your business in the center of a densely populated residential and medical corridor with strong daytime and evening foot traffic.
• Just steps from Bloomingdale’s flagship store (59th Street and Lexington Avenue), a world-famous luxury department store that draws thousands of daily shoppers.
• Minutes from Central Park (entrance at 59th Street and Fifth Avenue), Fifth Avenue luxury shopping (Bergdorf Goodman, Tiffany & Co., Cartier), Billionaires’ Row (57th Street), and The Plaza Hotel.
• Short walk to Sutton Place Park and the East River waterfront.

Medical & Institutional Proximity – A Healthcare Hub:

• Located within blocks of some of New York City’s most prestigious medical institutions:
• Weill Cornell Medical Center (68th Street and York Avenue)
• NewYork-Presbyterian Hospital (68th Street and York Avenue)
• Hospital for Special Surgery (HSS) — #1 in orthopedics nationwide (70th Street and York Avenue)
• Memorial Sloan Kettering Cancer Center (67th-68th Streets on York Avenue)
• Rockefeller University (66th-68th Streets on York Avenue)
• This concentration of world-renowned hospitals and research centers creates consistent, high-demand foot traffic from medical professionals, hospital employees, patients, families, and caregivers — all needing nearby services and amenities.

Spacious & Versatile Retail Layout:

• 1,058 SF of well-proportioned retail space — ideally sized for a medical or dental practice, urgent care center, physical therapy clinic, pharmacy, beauty salon, or specialty food shop.
• Attractive storefront with excellent street-level visibility on East 61st Street, a quiet but convenient residential block with steady local foot traffic.
• Functional floor plan suitable for exam rooms and reception area (medical practice), retail displays and checkout (pharmacy/market), or service stations (salon).
• Large windows providing abundant natural light — a valuable feature for patient-facing medical practices and wellness studios.
• Potential for back-of-house space, storage, or office areas depending on configuration.
• At $28.35 per square foot, this price reflects the premium nature of this location — competitive for this affluent medical corridor.

Excellent Transit Access:

• Moments from the Lexington Avenue / 59th Street subway station (4, 5, 6, N, R, W) , one of Manhattan’s busiest and most convenient transit hubs.
• Close to the 57th Street station (F, Q) , Fifth Avenue / 59th Street station (N, R, W) , and Roosevelt Island Tram (59th Street and Second Avenue).
• Multiple bus routes serve Second Avenue, Third Avenue, and 59th Street (M15, M31, M57, M101, M102, M103, Q32).
• Short walk to Grand Central Terminal (42nd Street) and Penn Station (34th Street).
• Convenient for medical professionals, patients, and families from all five boroughs, Westchester, Long Island, and New Jersey.

Affluent, High-Demand Customer Base:

• Medical professionals — thousands of doctors, nurses, researchers, and administrators employed at nearby world-class hospitals.
• Patients and families — patients seeking treatment at Weill Cornell, NY-Presbyterian, HSS, and MSK, plus their families, create consistent demand for medical practices, urgent care, pharmacies, and patient-serving retail (coffee shops, delis, gift stores, florists).
• Local residents — wealthy, established residents of Lenox Hill, Sutton Place, and the Upper East Side, including finance executives, medical professionals, lawyers, and philanthropists.
• Bloomingdale’s shoppers — thousands of daily shoppers at the iconic department store, many of whom pass through the surrounding neighborhood.
• Ideal for businesses such as:
• Medical or dental practice (primary care, pediatrics, dermatology, dentistry, orthodontics, ophthalmology)
• Urgent care or walk-in clinic
• Physical therapy or rehabilitation center
• Pharmacy or drugstore
• Beauty or nail salon
• Specialty food market or gourmet grocery
• Coffee shop or cafe (patient and staff-friendly)
• Optical or eyewear shop
• Hearing aid or audiology practice
• Florist or gift shop (hospital-adjacent)

Highlights:
✔ 1,058 SF of prime retail space in Lenox Hill / Upper East Side
✔ $30,000/month — premium location at $28.35 per square foot
✔ Attractive storefront on a quiet, tree-lined residential block
✔ Blocks from Weill Cornell, NY-Presbyterian, HSS, and Memorial Sloan Kettering
✔ Ideal for medical/dental practice, urgent care, pharmacy, or specialty retail
✔ Functional layout with potential for exam rooms, reception, and storage
✔ Large windows with abundant natural light
✔ Affluent, high-demand customer base — medical professionals, patients, residents, and Bloomingdale’s shoppers
✔ Excellent transit access — 4, 5, 6, N, R, W, F, Q trains

Conclusion:

252 E 61st Street offers an exceptional opportunity for healthcare providers, medical professionals, and small business owners seeking premium retail space in one of the Upper East Side’s most desirable medical corridors — Lenox Hill. With 1,058 SF of functional, flexible space, a prime East 61st Street location steps from world-class hospitals and Bloomingdale’s, and access to a loyal, high-demand customer base of medical professionals, patients, affluent residents, and shoppers, this property is perfect for medical and dental practices, urgent care centers, pharmacies, physical therapy clinics, or patient-serving retail concepts looking to thrive in the heart of Manhattan’s premier healthcare district.

Contact us today to schedule a private tour and secure this premier Upper East Side retail space!