Key Features:
Prime Upper East Side / Lenox Hill Location:
- Situated on East 69th Street, a quiet, tree-lined residential block in the heart of the Upper East Side’s Lenox Hill neighborhood — one of Manhattan’s most prestigious and sought-after residential areas.
- Located between First Avenue and York Avenue, two busy north-south corridors lined with retail, restaurants, pharmacies, and daily conveniences.
- Minutes from the East River and Carl Schurz Park (68th-70th Streets), a beloved waterfront green space attracting families, dog walkers, joggers, and children daily.
- Surrounded by a mix of luxury co-ops and condominiums, pre-war townhouses, and world-class medical institutions.
- Short walk to Second Avenue’s Q subway line, Third Avenue’s retail corridor, Lexington Avenue’s boutique shopping, and Madison Avenue’s luxury flagships.
Medical & Institutional Proximity – A Healthcare Hub:
- Located within blocks of some of New York City’s most prestigious medical institutions:
- Weill Cornell Medical Center (68th Street and York Avenue)
- NewYork-Presbyterian Hospital (68th Street and York Avenue)
- Hospital for Special Surgery (HSS) (70th Street and York Avenue) — #1 in orthopedics nationwide
- Memorial Sloan Kettering Cancer Center (67th-68th Streets on York Avenue)
- Rockefeller University (66th-68th Streets on York Avenue)
- This concentration of world-renowned hospitals and research centers creates consistent, high-demand foot traffic from medical professionals, hospital employees, patients, families, and caregivers — all needing nearby services and amenities.
Spacious & Versatile Retail Layout:
- 1,312 SF of generous retail space — perfectly sized for a medical practice, dental office, fitness studio, specialty market, or service-based business.
- Attractive storefront with good street-level visibility on a quiet residential block with steady foot traffic.
- Open floor plan with high ceilings, allowing for easy customization to fit various business needs — from exam rooms and reception areas to retail displays and fitness equipment.
- Large windows providing abundant natural light — a valuable feature for patient-facing medical practices and wellness studios.
- Potential for multiple private offices, exam rooms, a reception/waiting area, break room, and storage.
- At $22.86 per square foot, this price reflects the premium associated with a prime Upper East Side location in close proximity to world-class medical institutions.
Excellent Transit Access:
- Close to the 68th Street – Hunter College subway station (6) on Lexington Avenue (approximately a 10-minute walk).
- Short walk to the 72nd Street station (Q) on Second Avenue, providing a direct connection to Midtown and downtown via the Second Avenue Subway.
- Multiple bus routes serve First Avenue, York Avenue, 68th Street, and 72nd Street (M15, M31, M66, M72, M79-SBS).
- Convenient for Upper East Side residents, medical professionals, hospital employees, patients, and their families.
Affluent, Loyal & High-Demand Customer Base:
- The Lenox Hill neighborhood is home to some of New York City’s wealthiest and most established residents, including medical professionals, finance executives, lawyers, philanthropists, and families.
- The proximity to four world-class hospitals creates significant demand for medical and dental practices, urgent care centers, physical therapy clinics, pharmacies, and patient-amenity retail (e.g., coffee shops, delis, gift shops, florists, optical shops).
- Strong daytime foot traffic from hospital employees, home healthcare workers, residents, and patients/families seeking services and amenities.
- The neighborhood’s strong sense of community and loyalty to local businesses make it ideal for businesses that rely on repeat clientele and word-of-mouth referrals.
- Unlike the luxury retail corridors of Madison or Fifth Avenues, this location offers essential, everyday retail opportunities with less competition and more reasonable rents.
- Ideal for businesses such as:
- Medical or dental practice (primary care, pediatrics, dermatology, dentistry, orthodontics, ophthalmology)
- Urgent care or walk-in clinic
- Physical therapy or rehabilitation center
- Pharmacy or drugstore
- Boutique fitness or yoga studio
- Specialty food market or gourmet grocery
- Beauty or nail salon
- Pet supply or grooming
- Coffee shop or café (patient and staff-friendly)
- Optical or eyewear shop
- Hearing aid or audiology practice
- Florist or gift shop (hospital-adjacent)
Highlights:
✔ 1,312 SF of premium retail space on the Upper East Side
✔ $30,000/month — competitive at $22.86 per square foot for a medical-adjacent location
✔ Attractive storefront on a quiet, tree-lined residential block
✔ Blocks from Weill Cornell, NY-Presbyterian, HSS (#1 orthopedics), and Memorial Sloan Kettering
✔ Ideal for medical/dental practices, physical therapy, pharmacy, or fitness studio
✔ Open floor plan with high ceilings and abundant natural light
✔ Affluent, loyal local residential customer base plus hospital employees and patients
✔ Convenient transit access — 6 and Q trains, multiple bus routes
Conclusion:
345 E 69th Street offers an outstanding opportunity for healthcare providers and small business owners seeking premium retail space in one of the Upper East Side’s most desirable medical-adjacent locations. With 1,312 SF of flexible, light-filled space, a prime Lenox Hill address steps from four world-class hospitals, and access to an affluent, loyal, and high-demand customer base of residents, medical professionals, and patients, this property is perfect for medical and dental practices, physical therapy clinics, pharmacies, boutique fitness studios, or patient-serving retail concepts looking to thrive in the heart of Manhattan’s premier healthcare corridor.
Contact us today to schedule a private tour and secure this premier Upper East Side retail space!
