Retail

Flagship-Scale Commercial Opportunity in Midtown East – 300 East 46th Street
Address: 300 East 46th Street, New York, NY, 10017
Price: $120,000/month
Lease Type: Commercial Lease
Type: Office / Medical / Showroom / Institutional
Location: Urban – Midtown East / United Nations District
Square Feet: 10,541 SF
Building Class: B
Market Segment: Corporate HQ, Medical Facility, Embassy Use, Educational/Training Center

Property Overview:
Offering over 10,500 square feet of expansive commercial space, 300 East 46th Street delivers a rare opportunity to occupy a full-floor presence in the heart of Midtown East, just steps from the United Nations Headquarters, Grand Central, and major diplomatic and corporate institutions. This versatile space is ideally suited for government agencies, consulates, large medical practices, educational institutions, or corporate users seeking a prestigious and secure Manhattan address.

Key Features:

Strategic Midtown East Location

• Steps from the United Nations Plaza, Consulate Row, and top-tier hotels
• Surrounded by major law firms, NGOs, and international organizations
• Ideal for tenants requiring privacy, proximity to Midtown’s core, and global access

Expansive Layout with Flexibility

• 10,541 SF of contiguous space with full-floor identity
• Easily adaptable for clinical, academic, or corporate interior configurations
• Generous ceiling height, professional finishes, and ample natural light

Exceptional Transit Access

• Convenient to 4/5/6, 7, and S subway lines at Grand Central Terminal
• Easy access to Midtown buses, Metro-North, and major airports
• Centrally located for staff, clients, and international visitors alike

Highlights:

• $120,000/month for 10,541 SF of premium Midtown East commercial space
• Full-floor opportunity in professional building environment
• Ideal for medical, institutional, governmental, or corporate use
• High-profile location with excellent infrastructure and connectivity
• Long-term lease options available

Conclusion:
300 East 46th Street offers a high-capacity, high-impact space for businesses and organizations that demand both functionality and location. Whether you’re establishing a medical suite, international headquarters, training center, or specialized practice, this space delivers scalability, convenience, and prestige in one of New York’s most secure and internationally significant neighborhoods.

Contact us today to schedule a confidential tour and explore the potential.