380 Second Avenue – New York, NY 10010
Neighborhood: Gramercy / Kips Bay
Asking Rent: $80,000 / Month
Size: 20,000 Sq Ft
Use Type: Retail / Restaurant / Flagship / Medical / Fitness
For Lease
Property Overview
380 Second Avenue presents a high-exposure 20,000-square-foot corner-style commercial opportunity in one of Manhattan’s most high-density residential and nightlife corridors. With nonstop foot traffic, strong demographics, and premium visibility, this location is ideal for flagship retail, restaurant, café, medical, fitness, or national brand expansion.
This is a trophy Second Avenue retail address with unmatched branding potential.
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Layout & Interior Features
• 20,000 SF open street-level commercial layout
• Prime Second Avenue frontage
• Exceptional corner-style visibility potential
• Floor-to-ceiling glass storefront
• High ceilings for dramatic build-out
• Excellent signage and branding exposure
• Ideal for restaurant, café, medical, fitness, or flagship retail
• Heavy daytime + nightlife foot traffic
• Immediate occupancy potential
Building Features
• Modern mixed-use building
• Prime street-level retail positioning
• Strong surrounding tenant mix
• Excellent residential density
• High discretionary spending neighborhood
Location – Gramercy / Kips Bay
• One of Manhattan’s most active dining & retail corridors
• Surrounded by luxury residential towers, NYU medical campus & nightlife
• Steps from Gramercy Park, Flatiron & Union Square
• Immediate access to 4, 5, 6, L, N, Q, R subway lines
• One of NYC’s strongest restaurant & retail trade areas
• Exceptional long-term appreciation potential
Summary
380 Second Avenue delivers 20,000 SF of premium flagship commercial space at $80,000/month in a top-performing Manhattan retail corridor. With unmatched visibility, intense foot traffic, and elite neighborhood demographics, this property is ideal for high-volume restaurant groups, national retail brands, medical flagships, and experiential concepts seeking dominant market presence.
