Office

Affordable Full-Floor Commercial Space – 271 Madison Avenue, New York, NY 10016

Monthly Rent: $21,000
Size: 5,250 square feet
Type: Office / Medical / Education / Nonprofit / Creative Studio
Location: Midtown South – Murray Hill
Use: Ideal for private offices, clinical use, administrative headquarters, or training centers
Lease Type: Commercial lease

Property Overview:

271 Madison Avenue offers 5,250 square feet of full-floor commercial space in a well-maintained, classic Midtown office building. Perfect for budget-conscious tenants seeking a large footprint, this space offers flexibility, natural light, and a central location near Grand Central Terminal and major subway lines.

Key Features:

• 5,250 SF of full-floor space with flexible office layout
• Elevator access and lobby security
• Excellent value for Midtown South with only ~$4 per SF/month
• Ideal for professional services, medical offices, or creative use
• Windows on multiple sides for great natural light throughout the floor

Location & Accessibility:

Located between East 39th and 40th Streets, 271 Madison Avenue is just minutes from Grand Central Terminal, Bryant Park, and major subway lines including the 4/5/6, 7, and S. Ample dining, transit, and service amenities are steps away.

Highlights:

• $21,000/month for 5,250 SF – rare value in Midtown Manhattan
• Turnkey layout with reception, private offices, and open work areas
• Centrally located with excellent commuter access
• Flexible lease terms and immediate availability

Summary:

271 Madison Avenue offers a rare opportunity to lease full-floor commercial space in a central Manhattan location at exceptional value. With proximity to transit, ample square footage, and a professional setting, it’s ideal for growing businesses, nonprofits, or healthcare practices.

Contact us today to arrange a tour or request full leasing details.