The space features a generous, inviting frontage with excellent street-level visibility along East 38th Street, capturing the attention of the area’s dense population of residents, corporate professionals, and medical workers from nearby hospitals and institutions. Its expansive, open floorplan provides remarkable flexibility for a wide range of uses, from full-service dining and takeout establishments to fitness centers, urgent care clinics, or curated retail concepts. The interior offers a functional, move-in-ready environment with oversized windows that flood the space with natural light, while the adaptable layout can accommodate dining areas, prep kitchens, treatment rooms, private offices, or display zones as required.
Key Features
- Asking Rent: $24,500 / month
- Available Space: 1,440 SF
- Property Type: Ground-Floor Retail Storefront
- Lease Type: Direct Lease
- Building Class: Class B
- Ceiling Height: Approx. 10–11 FT
- Layout: Expansive, open floorplan ideal for restaurant, fitness, medical, or retail uses
- Condition: Well-maintained; ready for tenant fit-out and customization
- Frontage: Wide storefront with excellent street visibility and abundant natural light
- HVAC: Existing HVAC system; tenant-controlled
- Access: Direct sidewalk entry with secure storefront system
- Plumbing: Adequate plumbing and gas capacity suitable for food-service or medical use
- Neighborhood Highlights: Located in Murray Hill, surrounded by corporate headquarters, luxury residences, and world-class medical institutions
Neighborhood Highlights
Located between Second Avenue and Third Avenue, 300 E 38th Street places you in the heart of Murray Hill, one of Manhattan’s most centrally located and dynamic residential and commercial neighborhoods. Known for its tree-lined streets, pre-war architecture, and diverse population of young professionals, families, and longtime residents, Murray Hill offers a rare blend of urban energy and neighborhood charm.
The area is home to a thriving dining and nightlife scene, with acclaimed restaurants, cozy cafes, and lively bars along Third Avenue and Lexington Avenue, creating a vibrant and loyal local customer base. The neighborhood is also a major hub for medical and corporate institutions, with NYU Langone Medical Center, Bellevue Hospital, and the United Nations Headquarters all within close proximity, ensuring a steady flow of professionals, patients, and visitors throughout the day. Nearby landmarks include the iconic Chrysler Building, Grand Central Terminal, and the East River’s scenic waterfront promenades and parks, offering an array of recreational and cultural attractions just moments away.
Transportation is exceptionally convenient, with the 6 train at 33rd Street, the 4/5/6 and 7 trains at Grand Central-42nd Street, and the S shuttle at Grand Central all within easy walking distance. Multiple bus routes, including the M34, M15, M101, M102, and M103, provide seamless connectivity across Manhattan, Queens, and the Bronx, while the nearby FDR Drive offers convenient vehicular access to all parts of the city.
Summary
The 1,440 SF retail storefront at 300 E 38th Street, New York, NY 10016, is available for $24,500 per month under a direct lease. With its generous square footage, prime Murray Hill address, strong neighborhood demographics, and exceptional proximity to corporate offices, medical institutions, and world-class transportation, this property represents a compelling opportunity for restaurateurs, fitness operators, medical professionals, or retailers seeking a high-profile and accessible home in one of Manhattan’s most centrally connected and thriving neighborhoods.
