Retail

Prime Retail Space on First Avenue – 1133 1st Ave, Lenox Hill / Upper East Side

Address: 1133 First Avenue, New York, NY, 10065
Price: $40,000/month
Square Feet: 1,400 SF
Type: Retail Space

Property Overview:

Located on First Avenue in the prestigious Lenox Hill neighborhood of the Upper East Side, 1133 First Avenue offers 1,400 SF of prime retail space at a premium price befitting this high-traffic, affluent medical and residential corridor. Ideal for medical and dental practices, urgent care centers, physical therapy clinics, pharmacies, fitness studios, or patient-serving retail. Situated between East 61st Street and East 62nd Street, this space benefits from proximity to world-class hospitals (Weill Cornell, NY-Presbyterian, HSS, Memorial Sloan Kettering), luxury residential buildings, and some of the city’s best dining, shopping, and transit.

Key Features:

Prime Lenox Hill / Upper East Side Location:

• Situated on First Avenue, a busy north-south thoroughfare serving the Lenox Hill neighborhood of the Upper East Side — one of Manhattan’s most desirable, prestigious, and convenient neighborhoods, known for its pre-war architecture, tree-lined streets, strong sense of community, and proximity to world-class medical institutions and luxury shopping.
• Located between East 61st Street and East 62nd Street, placing your business in the center of one of Manhattan’s most active medical and residential corridors.
• Just steps from Weill Cornell Medical Center (68th Street and York Avenue), NewYork-Presbyterian Hospital, Hospital for Special Surgery (HSS) — #1 in orthopedics nationwide — and Memorial Sloan Kettering Cancer Center.
• Minutes from Central Park (entrance at 59th Street and Fifth Avenue — a 10-minute walk), Bloomingdale’s flagship store (59th Street and Lexington Avenue), Madison Avenue luxury shopping (Chanel, Dior, Hermès, Prada), and Billionaires’ Row (57th Street).

Medical & Institutional Proximity – A Healthcare Hub:

• Located within blocks of some of New York City’s most prestigious medical institutions:
• Weill Cornell Medical Center (68th Street and York Avenue)
• NewYork-Presbyterian Hospital (68th Street and York Avenue)
• Hospital for Special Surgery (HSS) — #1 in orthopedics nationwide
• Memorial Sloan Kettering Cancer Center
• Rockefeller University
• This concentration of world-renowned hospitals and research centers creates consistent, high-demand foot traffic from medical professionals, hospital employees, patients, families, and caregivers — all needing nearby medical services, pharmacies, and patient-serving retail.

Spacious & Versatile Retail Layout:

• 1,400 SF of generous retail space — ideally sized for a medical or dental practice, urgent care center, physical therapy clinic, pharmacy, fitness studio, or patient-serving retail.
• Attractive storefront with excellent street-level visibility on First Avenue, a busy corridor with constant pedestrian and vehicular flow.
• Functional floor plan suitable for exam rooms and reception area (medical practice), retail displays and checkout (pharmacy), or fitness equipment and studio space (gym).
• Large windows providing abundant natural light — a valuable feature for patient-facing medical practices and wellness studios.
• Potential for back-of-house space, storage, or office areas depending on configuration.
• At $28.57 per square foot, this price reflects the premium nature of this location — competitive for this high-demand medical corridor.

Excellent Transit Access:

• Moments from the Lexington Avenue / 59th Street subway station (4, 5, 6, N, R, W) , one of Manhattan’s busiest and most convenient transit hubs.
• Close to the 57th Street station (F, Q) , 53rd Street station (E, M) , and Roosevelt Island Tram (59th Street and Second Avenue).
• Multiple bus routes serve First Avenue, Second Avenue, and 61st Street (M15, M31, M57, M101, M102, M103, Q32).
• Short walk to Grand Central Terminal (42nd Street) and Penn Station (34th Street).
• Convenient for medical professionals, patients, and families from all five boroughs, Westchester, Long Island, and New Jersey.

Affluent, High-Demand Customer Base:

• Medical professionals — thousands of doctors, nurses, researchers, and administrators employed at nearby world-class hospitals.
• Patients and families — patients seeking treatment at Weill Cornell, NY-Presbyterian, HSS, and MSK, plus their families, create consistent demand for medical practices, urgent care, pharmacies, and patient-serving retail.
• Local residents — wealthy, established residents of Lenox Hill, the Upper East Side, and surrounding neighborhoods.
• Ideal for businesses such as:
• Medical or dental practice (primary care, pediatrics, dermatology, dentistry, orthopedics)
• Urgent care or walk-in clinic
• Physical therapy or rehabilitation center
• Pharmacy or drugstore
• Medical imaging or lab services
• Vision care or optical shop
• Hearing aid or audiology practice
• Wellness or nutrition center
• Medical supply or equipment store

Highlights:
✔ 1,400 SF of prime retail space on First Avenue in Lenox Hill
✔ $40,000/month — premium location at $28.57 per square foot
✔ Attractive storefront with excellent visibility on a busy medical corridor
✔ Steps from Weill Cornell, NY-Presbyterian, HSS, and Memorial Sloan Kettering
✔ Ideal for medical/dental practice, urgent care, physical therapy, or pharmacy
✔ Functional layout with potential for exam rooms, reception, and storage
✔ Large windows with abundant natural light
✔ Affluent, high-demand customer base — medical professionals, patients, and residents
✔ Excellent transit access — 4, 5, 6, N, R, W, F, Q, E, M trains, Grand Central

Conclusion:

1133 First Avenue offers a prime opportunity for healthcare providers seeking premium retail space in one of the Upper East Side’s most desirable medical corridors — Lenox Hill, the heart of Manhattan’s premier healthcare district. With 1,400 SF of functional, flexible space, a prime First Avenue location steps from world-class hospitals, and access to a loyal, high-demand customer base of medical professionals, patients, and families, this property is perfect for medical and dental practices, urgent care centers, physical therapy clinics, or pharmacies looking to thrive in a location where healthcare is the primary industry — at a premium price befitting this prime location.

Contact us today to schedule a private tour and secure this premier Upper East Side retail space!