Retail

Affordable Retail Space on East 80th Street – 223 E 80th Street, Yorkville / Upper East Side

Address: 223 E 80th Street, New York, NY, 10075
Price: $15,000/month
Square Feet: 1,948 SF
Type: Retail Space

Property Overview:

Located on East 80th Street in the Yorkville neighborhood of the Upper East Side, 223 E 80th Street offers 1,948 SF of spacious retail space at exceptional value for this desirable residential neighborhood. Ideal for medical and dental practices, physical therapy centers, veterinary clinics, pet supply stores, daycares, fitness studios, art galleries, or service-based businesses. Situated between Second Avenue and Third Avenue, this space benefits from a strong local residential customer base, proximity to major medical institutions and Carl Schurz Park, and excellent transit access.

Key Features:

Prime Yorkville / Upper East Side Location:

• Situated on East 80th Street, a quiet, tree-lined residential block in the heart of Yorkville — one of the Upper East Side’s most charming and community-oriented neighborhoods, known for its pre-war architecture, strong sense of community, and excellent value.
• Located between Second Avenue and Third Avenue, placing your business in the center of the neighborhood’s vibrant retail and residential corridors.
• Just steps from Carl Schurz Park (86th Street and East End Avenue), a beloved waterfront green space featuring walking paths, playgrounds, dog runs, and stunning East River views — home to Gracie Mansion.
• Minutes from the East River Promenade, offering beautiful waterfront walking, running, and biking paths — attracting families, joggers, and dog walkers daily.
• Close to Gracie Mansion, Asphalt Green (a community fitness and sports center), and John Jay Park.
• Short walk to Third Avenue and Second Avenue retail corridors, offering a wide range of dining, shopping, and services.

Medical & Institutional Proximity:

• Located within easy reach of some of New York City’s most prestigious medical institutions:
• Weill Cornell Medical Center
• NewYork-Presbyterian Hospital
• Hospital for Special Surgery (HSS) — #1 in orthopedics nationwide
• Memorial Sloan Kettering Cancer Center
• This concentration of world-renowned hospitals creates consistent demand for medical and dental practices, physical therapy clinics, pharmacies, urgent care centers, and patient-serving retail.

Spacious & Flexible Retail Layout:

• 1,948 SF of generous retail space — well-suited for medical practices, therapy centers, veterinary clinics, daycares, fitness studios, or neighborhood service businesses.
• Attractive storefront with good street-level visibility on East 80th Street, a quiet residential block with steady local foot traffic.
• Practical layout with potential for a reception area, multiple private exam or treatment rooms, a break room, and storage.
• Large windows providing abundant natural light — a valuable feature for patient-facing medical practices and wellness studios.
• At $7.70 per square foot, this represents exceptional value for retail space on the Upper East Side — significantly below the neighborhood average.

Exceptional Value – Under $7.75 per Square Foot:

• At $7.70 per square foot, this is an exceptional value for retail space on the Upper East Side, one of Manhattan’s most desirable residential neighborhoods.
• The combination of price, location, space, and neighborhood quality makes this an outstanding opportunity for healthcare providers and small business owners.

Excellent Transit Access:

• Close to the 86th Street subway station (4, 5, 6) on Lexington Avenue (approximately a 10-minute walk), providing direct access to the entire East Side of Manhattan and Grand Central Terminal.
• Short walk to the 86th Street station (Q) on Second Avenue, providing access to the Second Avenue Subway.
• Multiple bus routes serve Second Avenue, Third Avenue, and 79th/80th Streets (M15, M31, M79-SBS, M86-SBS).
• Convenient for Upper East Side residents, medical professionals, hospital employees, patients, and their families.

Vibrant, Family-Friendly Neighborhood:

• Yorkville is known for its quiet, tree-lined streets, strong sense of community, family-friendly atmosphere, and excellent value — one of the few neighborhoods in Manhattan where businesses can still find affordable retail space without sacrificing quality of life.
• Carl Schurz Park is a neighborhood gem, offering beautiful waterfront green space, walking paths, dog runs, playgrounds, and stunning East River views. The park also hosts community events and farmers’ markets throughout the year.
• The East River Promenade offers beautiful walking, running, and biking paths with stunning views of the Queensboro Bridge, Roosevelt Island, and Long Island City.
• The neighborhood is home to a mix of longtime residents, young families, medical professionals (due to proximity to major hospitals), and young professionals.
• Third Avenue and Second Avenue offer a wide range of dining options, from casual pizza joints to upscale Mediterranean and sushi restaurants.
• Fairway Market (86th Street and Second Avenue) and Morton Williams (86th Street and First Avenue) provide convenient grocery shopping.
• Asphalt Green (91st Street and York Avenue) offers a fitness center, swimming pool, and sports programs for all ages.

Ideal Business Types:
This spacious, affordable retail space is perfect for:

• Medical or dental practice (primary care, pediatrics, dermatology, dentistry, orthodontics)
• Physical therapy or rehabilitation center
• Urgent care or walk-in clinic
• Pharmacy or drugstore
• Veterinary clinic or pet supply store
• Daycare or early childhood center
• Art gallery or frame shop
• Boutique fitness or yoga studio
• Beauty or nail salon
• Specialty food market or grocery
• Dry cleaner or laundromat
• Tutoring or test prep center

Highlights:
✔ 1,948 SF of affordable retail space in Yorkville / Upper East Side
✔ $15,000/month — exceptional value at just $7.70 per square foot
✔ Attractive storefront on a quiet, tree-lined residential block
✔ Walking distance to Weill Cornell, NY-Presbyterian, HSS, and Memorial Sloan Kettering
✔ Ideal for medical/dental practices, physical therapy, veterinary clinic, daycare, or gallery
✔ Practical layout with potential for exam rooms, reception, and storage
✔ Large windows with abundant natural light
✔ Loyal, local residential customer base plus hospital employees and patients
✔ Convenient transit access — 4, 5, 6, Q trains and multiple bus routes

Conclusion:

223 E 80th Street offers an outstanding opportunity for healthcare providers, small business owners, and entrepreneurs seeking affordable, spacious retail space in one of the Upper East Side’s most charming and desirable neighborhoods — Yorkville. With 1,948 SF of practical, flexible space, a prime location on a quiet residential block steps from Carl Schurz Park, and access to a loyal, high-demand customer base of residents, medical professionals, and patients, this property is perfect for medical and dental practices, physical therapy clinics, veterinary offices, daycare centers, art galleries, or neighborhood service businesses looking to thrive in a high-quality Manhattan neighborhood — all at an exceptional value of just over $7.70 per square foot.

Contact us today to schedule a private tour and secure this exceptional Upper East Side retail space!