Retail

For Lease – 255 East 39th Street, New York, NY 10016

Asking Rent: $40,000 / Month
Available Space: 1,150 SF
Property Type: Retail / Medical Office
Lease Type: Direct Lease
Location: Midtown East / Murray Hill, Manhattan

Property Overview

Introducing 255 East 39th Street, a 1,150-square-foot ground-floor retail or medical space available for $40,000 per month, ideally located at the crossroads of Midtown East and Murray Hill. This corner property offers prime visibility with wraparound glass frontage and heavy foot traffic from nearby residential towers, offices, and medical facilities.

The space features a bright, modern storefront, open interior layout, and high ceilings, suitable for boutique retail, wellness concepts, or medical tenants seeking an upscale, accessible Midtown location. Its proximity to major hospitals, corporate offices, and luxury residential buildings makes it an excellent choice for high-end service providers or destination retail users.

Key Features

• Asking Rent: $40,000 / Month
• Available Space: 1,150 SF
• Property Type: Retail / Medical Office
• Lease Type: Direct Lease
• Frontage: Prominent glass corner façade on East 39th Street
• Ceiling Height: Approx. 11 FT
• Layout: Open floor plan with rear restroom / storage
• Condition: Move-in ready
• HVAC: Tenant-controlled
• Signage: Exceptional street visibility on prime Midtown corridor
• Access: Street-level entry with ADA accessibility
• Building Type: Mixed-use building with residential above

Neighborhood Profile

Location Advantage:
Strategically located near Second Avenue and Tunnel Exit Street, 255 East 39th Street benefits from excellent visibility and steady traffic from both residents and commuters. The area is minutes from Grand Central Terminal, providing access to major subway lines and Metro-North trains. It’s also near several major medical and office hubs, including NYU Langone Health, Tudor City, and United Nations Headquarters.

Lifestyle Appeal:
The Murray Hill / Midtown East corridor is known for its blend of professional, medical, and residential activity. The neighborhood supports strong daytime and evening populations, offering consistent exposure for retail, health, or service-based tenants. Nearby amenities include dining, boutique fitness, and high-density housing developments.

Summary

The 1,150 SF ground-floor commercial space at 255 East 39th Street, New York, NY 10016, is available for $40,000 per month on a direct lease. With corner frontage, modern interiors, and prime Midtown East visibility, this property is ideally suited for medical offices, boutique retailers, or wellness operators seeking strong exposure in a high-traffic, high-income Manhattan location.