Retail

For Lease – 643–645 Second Avenue, New York, NY 10016

Asking Rent: $30,000 / Month
Available Unit Size: 1,100 SF Retail
Property Type: Ground-Floor Storefront Retail
Lease Type: Direct Lease
Location: Murray Hill / Midtown East, Manhattan, New York

Property Overview

Welcome to 643–645 Second Avenue, a 1,100-square-foot retail storefront offered at $30,000 per month, ideally situated in the heart of Murray Hill — one of Midtown East’s most established and energetic mixed-use neighborhoods.

This high-visibility corner retail space offers expansive glass frontage, high ceilings, and an open interior layout, perfectly suited for restaurants, boutique retailers, cafés, or wellness operators. Surrounded by high-rise residential towers, medical offices, and hotels, this location benefits from both local and commuter foot traffic throughout the day and evening.

Key Features

• Asking Rent: $30,000 / Month
• Available Space: 1,100 SF Retail
• Property Type: Ground-Floor Storefront Retail
• Lease Structure: Direct Lease
• Frontage: Corner glass façade with exceptional visibility on Second Avenue
• Ceiling Height: Approx. 12 feet
• Layout: Open floor plan with flexible build-out potential
• Neighborhood: Murray Hill / Midtown East – dense residential and office population
• Transit Access: Near 33rd Street (6) subway station and Grand Central Terminal (4/5/6/7/S, Metro-North)

Market Profile

Location Advantage:
Second Avenue in Murray Hill provides continuous pedestrian flow from residents, medical professionals, and corporate workers, creating a reliable base for retail, food, and service operators.

Lifestyle Appeal:
Surrounded by popular dining destinations, boutique gyms, and professional offices, this corridor offers strong day-to-night activity ideal for hospitality and neighborhood-oriented retail.

Competitive Advantage:
At $30,000/month for 1,100 SF, this property delivers rare corner exposure and branding opportunity in a proven Midtown East submarket — a premium option for tenants seeking visibility and accessibility.

Summary

The 1,100 SF retail space at 643–645 Second Avenue, New York, NY 10016, is available for $30,000/month.
Featuring expansive glass frontage, an open interior layout, and a prime Murray Hill location, this property is ideal for restaurants, cafés, boutique retailers, or wellness users looking for a highly visible Midtown East presence.